Radioimmunotherapy—time to be upfront and fractionated?
نویسندگان
چکیده
منابع مشابه
Microenvironment and Immunology Acquired Resistance to Fractionated Radiotherapy Can Be Overcome by Concurrent PD-L1 Blockade
Radiotherapy is a major part in the treatment of most common cancers, but many patients experience local recurrence with metastatic disease. In evaluating response biomarkers, we found that low doses of fractionated radiotherapy led to PD-L1 upregulation on tumor cells in a variety of syngeneic mousemodels of cancer. Notably, fractionated radiotherapy delivered in combination with aPD-1 or aPD-...
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ژورنال
عنوان ژورنال: Nature Reviews Clinical Oncology
سال: 2013
ISSN: 1759-4774,1759-4782
DOI: 10.1038/nrclinonc.2013.236